Genomic second opinions for patients and families with complex or unanswered health questions

Physician-supervised review of existing genetic results and clinical history to help clarify possible diagnoses, next steps, confirmatory testing, referrals, and medication-related genomic findings.

Could genomic review be helpful?

Examples of clinical presentations that may benefit from genomic review.

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Autism and neurodevelopmental differences

Nonverbal autism; Asperger’s syndrome; autism spectrum disorders; pervasive developmental disorder not otherwise specified (PDD-NOS); and childhood disintegrative disorder.

ADHD, anxiety, depression, or treatment-resistant symptoms

Attention deficit hyperactivity disorder (ADHD); generalized anxiety disorder (GAD); obsessive-compulsive disorder (OCD); persistent major depressive disorder (MDD); and bipolar disorder with treatment-resistant depression.

Medication side effects, drug sensitivity, or pharmacogenomic concerns

Pharmacogenomic issues, including variations in enzymes affecting drug metabolism; adverse drug reactions such as Stevens-Johnson syndrome or drug-induced lupus; and multiple drug allergies or sensitivities.

Alzheimer’s/APOE questions in an appropriate clinical context

APOE genotyping may be relevant in selected patients being evaluated for Alzheimer’s disease risk or amyloid-targeting therapy risk stratification. Results should be interpreted in the context of clinical evaluation and should not be used alone to diagnose dementia.

Seizures and neurogenetic conditions

Down syndrome; fragile X syndrome; Rett syndrome; Lennox-Gastaut syndrome; and Dravet syndrome.

Skin, sensory, digestive, or multisystem symptoms

Eczema (atopic dermatitis); psoriasis; sensory processing disorder; irritable bowel syndrome (IBS); Crohn’s disease; and celiac disease.

Hereditary cancer risk assessment

Genomic review may be helpful for individuals or families with a personal history of cancer, cancer diagnosed at an unusually young age, multiple primary cancers, or a family history of breast, ovarian, colorectal, endometrial, pancreatic, prostate, melanoma, or other cancers. The purpose is to assess whether an inherited cancer predisposition syndrome may be relevant and whether genetic counseling, confirmatory testing, or referral to an appropriate cancer specialist should be considered.

Why choose a physician-supervised genomic review?

Most genomic data interpretation services rely on software engineers — we rely on physicians

Physician-led expertise

Unlike most genetic testing services that rely on software engineers and automated reports, our interpretation is led by physicians trained in clinical genomics. We connect your DNA results to your symptoms and your health history to provide real medical decision support.

Clinical integration and personalization

At the Center for Neuroscience and Genomic Medicine, we don’t just identify mutations — we interpret them in context. We evaluate the clinical relevance of each variant, generate genomic differential diagnoses, and provide rationale for confirmatory laboratory tests, imaging, specialist referrals, and lifestyle changes based on your unique profile.

Comprehensive, clinically focused review

Our review is not limited to ACMG-recommended actionable genes. We interpret genomic findings in the context of the patient’s clinical presentation and, when clinically appropriate, also review ACMG-recommended actionable genes — a curated set of genes associated with conditions that may be preventable or treatable when identified early, including certain cancers, heart disorders, and metabolic diseases.

Clear, actionable results

We translate complex genetic data into simple, meaningful decision-support insights. Our reports include clear next steps — not vague summaries or variant lists — and our AI tools allow for interactive exploration of data when desired.

Center for Neuroscience and Clinical Genomics

Dr. Andrius Baskys, MD, PhD

Clinic Founder and Medical Director

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Dr. Andrius Baskys is the founder and Medical Director of the Center for Neuroscience and Genomic Medicine. He is board-certified by the American Board of Psychiatry and Neurology and specializes in precision psychiatry and neurogenomics. Dr. Baskys completed his residency at the University of Toronto, a clinical fellowship at McMaster University, postdoctoral research at the University of California, San Francisco and holds Graduate Certificate in Clinical Genomics from NHS, UK.

Services

Dr Baskys provides comprehensive evaluation and personalized management for a wide spectrum of neuropsychiatric and neurodevelopmental conditions. He specializes in complex and often overlapping presentations, including Autism spectrum disorders (including adult autism and Asperger’s syndrome), Intellectual and developmental delays, Psychotic disorders, Neuropsychiatric conditions, Memory disorders, and screening for hereditary cancer syndromes.

Dr Baskys integrates clinical expertise with advanced genomic testing, including next-generation DNA sequencing, to support more accurate diagnosis and individualized treatment planning.

How our services are structured

MoodNote LLC develops and operates genomic data analysis, interpretation, reporting, and educational tools, including bioinformatics workflows, report-generation systems, and non-clinical decision-support technology. GenomeDDx™ is a trademark owned by MoodNote LLC. MoodNote LLC and MyGenePortal.com do not provide medical diagnosis, medical treatment, direct patient care, or emergency medical services. Medical services, if provided, are performed only by appropriately licensed clinicians or clinical organizations.

Center for Neuroscience and Genomic Medicine is a physician-led clinical service focused on genomic second opinions for patients with complex neurological, neurodevelopmental, psychiatric, and multisystem conditions. Clinical consultations, medical advice, diagnosis, treatment recommendations, medication decisions, referrals, and follow-up planning are provided only through the Center or by the patient’s own treating clinicians.

MyGenePortal.com is the online platform through which patients, families, and clinicians may learn about available services, submit general inquiries, access reports or genomic information when appropriate, and interact with genomic interpretation tools. MyGenePortal is a technology and communication platform; it is not a medical clinic.

This structure allows genomic data analysis and clinical consultation to remain clearly separated. Reports generated through MyGenePortal or MoodNote are intended to support discussion with licensed clinicians and should not be used as the sole basis for diagnosis, treatment, medication changes, or other medical decisions. A physician-patient relationship is established only after appropriate intake, consent, acceptance for care, and clinical consultation through the Center for Neuroscience and Genomic Medicine or another licensed healthcare provider.

Location

Dr Baskys provides Telemedicine consultations and consultations to referring physicians for complex cases.

Start with a free preliminary case screen

This no-cost initial review helps determine whether a comprehensive genomic second opinion is likely to be useful. Please use the contact form for general inquiries or to request next-step information.

Are you a patient, clinician or someone requesting free case screen?*

Important Information About this Form

This form is not HIPAA-compliant. Please do not include any personal health information (PHI), such as medical history, diagnoses, symptoms, medications, or test results. Use this form only for general inquiries or appointment requests. Do not upload or send any files or medical documents with this form. After your inquiry is reviewed, you will receive detailed instructions if secure file upload is appropriate.

Disclaimer: Submitting this form does not establish a physician-patient relationship. This site is for educational and informational purposes only and does not provide medical advice or treatment. Please consult a licensed healthcare provider in your jurisdiction for medical care.

Emergency Notice: If you are experiencing a psychiatric or medical emergency, do not use this form. Call 911 or go to your nearest emergency room.

NOTE: Patients located in the US states other than CA and MI will require a locally licensed provider referral.

CNGM

Center for Neuroscience and Genomic Medicine

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